Mathematical analysis of a lymphatic filariasis model with quarantine and treatment
نویسندگان
چکیده
BACKGROUND Lymphatic filariasis is a globally neglected tropical parasitic disease which affects individuals of all ages and leads to an altered lymphatic system and abnormal enlargement of body parts. METHODS A mathematical model of lymphatic filariaris with intervention strategies is developed and analyzed. Control of infections is analyzed within the model through medical treatment of infected-acute individuals and quarantine of infected-chronic individuals. RESULTS We derive the effective reproduction number, [Formula: see text] and its interpretation/investigation suggests that treatment contributes to a reduction in lymphatic filariasis cases faster than quarantine. However, this reduction is greater when the two intervention approaches are applied concurrently. CONCLUSIONS Numerical simulations are carried out to monitor the dynamics of the filariasis model sub-populations for various parameter values of the associated reproduction threshold. Lastly, sensitivity analysis on key parameters that drive the disease dynamics is performed in order to identify their relative importance on the disease transmission.
منابع مشابه
Lymph Node Enlargement in Neck Filariasis as a Rare Cause: A Case Report
Lymphatic filariasis is endemic to tropical countries and is the most common cause of acquired lymphedema in the world. Wuchereria bancrofti is the main etiological agent responsible. While the presentation of filariasis in limbs is common, isolated presentation as a single enlarged lymph node in the neck is very rare. We describe a 48-year-old Indian woman, who presented with a hard lymph node...
متن کاملFuzzy Sliding Mode Controller Design and Analysis of an SQEIAR Epidemic Model for COVID-19 to Determine the Quarantine Rate
According to the global prevalence of coronavirus (COVID-19) pandemic, mathematical models can predict and control the dynamic behavior of the pandemic. Therefore, in this study, a comprehensive model is considered to examine the trend of COVID-19 based on Susceptible, Exposed, Infected (Symptomatic and Asymptomatic), and Recovered individuals. In the absence of a curative treatment or vaccinat...
متن کاملAdvances and challenges in predicting the impact of lymphatic filariasis elimination programmes by mathematical modelling
Mathematical simulation models for transmission and control of lymphatic filariasis are useful tools for studying the prospects of lymphatic filariasis elimination. Two simulation models are currently being used. The first, EPIFIL, is a population-based, deterministic model that simulates average trends in infection intensity over time. The second, LYMFASIM, is an individual-based, stochastic m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 17 شماره
صفحات -
تاریخ انتشار 2017